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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f0bcf36ecc4942490361e3be14832f20fa3dace523eb0ff51145d42ed4d18eb' 
  AND token = 'S8L3P8X/faueRFEDO3/RyGA+t/sqbOK8rFcZT9ky/zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}