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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c13ebc9e5225b395d07974edde45b7ff89fdefab65a953fe39401fb4290a332a' 
  AND token = '5kVe8caH2GpnCznRYpE9rZC1XwRrrGdrqZ1DCo2sJ1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}