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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c308ef2de6b176e9f460082f4cad41989c343b7743200ba1e45dc1843b14526' 
  AND token = 'r2/oi+2edL/xjntsYjLNOOwJU9SBCLif7Pa5OcRQ3hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}