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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a83d7f6bf621922871638c8e1b7b8ad575b32490483b9e881d8b35bffaa0081c' 
  AND token = '5TmZQUS1r/LUduX6BdPutUsiEL1KA0GmMGr7JguWEHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}