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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68bd08b4509bb2714188ebdecf52e1d304195dcae781592b5fe818e12cdb2374' 
  AND token = 'DSG2u//6PpSvzF1CmbUzx9Hoz3zNcIED4i8DDsP0LxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}