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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23de6b202e040b7781f2fe149213651e9bef29947e8a4912ad1f534a674fbfd9' 
  AND token = 'bb9WIk34MiRcsMfKk6bMrpOIfGGkfx+DeAQXa5VU1EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}