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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4eecbe4bf38f7f985554402d6d6dbbd8706f6973f40ec3b6560dbd17b1e0a97' 
  AND token = '6QWU+i3DIlsXxoLmk+m6wrMklSAx27P1Si8pmJccMT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}