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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc65d6ad7726fd974b9ab7102f09d0e908b17fa9e8b22cbea749e5070476120' 
  AND token = '8FnCLWL+67vga2wCHAboBxRVJa8KZ9pbWOOg7IrQ1f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}