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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0214d9753be0b5da73082837d07646c366cc85845e003e9ef8cd6a435f0ce154' 
  AND token = 'i6XUAoAxiqI5WwZF8Y37ZBPibLN1qjmse6atb7XHz0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}