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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '673536d41184f6417cf8002c1cbb4c92be4c7470ada292408740650be4551ff0' 
  AND token = 'Y0VuL7ZqYlmO4MMG8Cn2R3BOKTSouezUcn6UihpBirA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}