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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f4bb82bd034b6e53d740dcd6a443ceeb0d1ade369df77bac35f79fa3445857' 
  AND token = 'EHlfhQOWCFjG0uMHfS2bHmaHYLl9W6hNmtpQTcgJ96o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}