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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1203a25f96d8570804b31ff37b73f9252d78bc1564816e68b903f77e062ed90' 
  AND token = 'czpqKIi8yyd3bLIKh3/qVgGaouauqPEX2jmdM4V3a9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}