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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57af7f3bac4f18b5d6f48efeedfbc37c20bc3f06f7e6a80185d81caea968716e' 
  AND token = 'whIHxQOM4GOkKw/Qr9qaSqXdkEQV6YEV0bRNdn/c10o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}