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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e72188c298ab9639f0e25a4aea3e03d1c3bb92861721c2ec30f1feed8b549a' 
  AND token = 'ocSjNOan32xH4W9QbuvrdnYu0ZLs5miNb2bUoQRBFMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}