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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e315c58f8e6f906f2462b1614c4ba45e411d909ddc76689243ee3a1c2647829' 
  AND token = 'JrB5UCmlTvlqQU3SgMtt+XuJEbdcernsJ/ciNGI0Joo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}