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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d048c42b0cb2d4390e1fa88daccb9f2460b84d4d725e44ad3cdc3828240e631' 
  AND token = '4KIFKm/xzC+q//1OHJSBiIAoZgEZuX8QuT/Ar8wAzrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}