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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4786ea1ce402f7cae9d12f5dbc7f26c377684b484e954d7636129a1a30626f5' 
  AND token = '0L6bqjKUL4rXbonllU81YiQHoeic+59zhtNlJywRF2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}