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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478a36c90f1c0cf237d5d55e389f92c88c3470ec51dcc6cc3a1bacfdb0439985' 
  AND token = 'GugKwpgQKamRV5D/54twEx3T0O2Y03G/hs1vpCmGLr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}