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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a0dd39d8544d6b569305c7c57b3d50619e9b4d3f7840dd4ec47aee52c79a12' 
  AND token = '0d5tW9ufeMNeveCFqeTaHsbH89oYbBoOTVZNVUXQrmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}