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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2240f399b9dd8705533ce970a6c9846c1e8713f4fc3d3e1081435392b8bf376' 
  AND token = 'eIG73ZnmKbL2jfrmO413dN+hVOP3Ob7yIAAxvk+Q4Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}