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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '512b7cd96f40a9d60b558e3f6e15ad8a8b1bfbf13c81472e9cdad684a2e33898' 
  AND token = '5ipuEaN8ESFGyfqOJ1nJmRH58K4VMtoJK2xgJ4RskjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}