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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbff523d469ee87a756dc8e678ddae10aa650b8d8ef3e9d8c6e526cf7be4af57' 
  AND token = '0Rt3aSQhhO0EH5BF2WyNo+0xRD5zAOtmwmoYzsov85k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}