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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b48adff0cc5aa7e7b70d6148e414b617c4520e2954312fea5e0749d8d9ac6f5' 
  AND token = 'lomo1ADiKJXvDgHfajg2LvT0dgeuvycyIHHnXyrxjnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}