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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1bf1e9d21ca57979c908ead37ee63a18d27642dec5860e0b0c1ce36535d789' 
  AND token = 'e459g4W1I4+X8St43Mof5vbFiDpLicKAWQXPaduIKQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}