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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0849c5e883e88a13da6540e9c43f31826c180ff5c1ea75c46bac27f13832e840' 
  AND token = 'JDS66BoFfWMmPfBI1vUv38TQ5zk/xjduPmGf6N5gMb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}