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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e181fe8418e035613c3f5c1bc463badf14ed4cea6a1bc419d2adc15b64121fb' 
  AND token = 'QXhF/fyXdxOMri1xLcuBt9zvO4nmg5idEY6a8w7B8NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}