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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163ed8da1335e1828ab7446471cb5b012869b7cdaee62e4dc4b2822f7ff56e81' 
  AND token = 'RBC230bOporY7jjTyk3e3aq9s7UqjNxF+zvQObf6F38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}