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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af15e6cae476607a814cc82ff6525c84b0ec65e0357c5f37d184ebb6c5d05c43' 
  AND token = '3TlV8xkxBUuwY7TxmT+UPiPY2TIZqomSwxIT9dZZ1hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}