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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726a7dd588940e2abb56ddf865c5e56f78c1e1011a1e40b1a6a43d8065cef21d' 
  AND token = 'DviwEbVRR/17RaWYjkmJB8F8iuztmIoT6n9iqPzuCYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}