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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfadacecdcd630a1910fde6deb29baf81945f3248a0f0c57d0d5f7883db2afdd' 
  AND token = '/ZXL+s21oJtS9udI6WRe8sNRVYhGJMS0LcrzufEPIP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}