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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18cce4c5279f33be89d0c656bedc90d9842522c84cc6550d4e2bf55a34e5b052' 
  AND token = '3kDTAr45GOYb4iz8wZ1gKbof7uwzaTbQexnmalOgLCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}