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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51281b08fb0411f7217a6be5831918a7aa5de8cdf3d8086b3aaf94a50496c12c' 
  AND token = '8JldRxPiEHKKW9Ucr2LVhG3ArL77IviacEyojqbj0io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}