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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9025ca1d81f9d8034802a2b2bdded70be0593cff709fd6f1939f0e03123d1a7' 
  AND token = 'BLX93N1T0FKiH/CstFsdUVAdXVlwW4zDlujRth6LthQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}