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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e594be8f4e15524e6b4bd2af13134bf232a93cbabc8234fe557373e42fc0914a' 
  AND token = 'aX/3WdnhToQAOHzFhHFZiJdgY44P4FwAla8d3+FGkuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}