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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f11807e420e682f22ecbbfa016f1dedfe0df06c818d482d9b3a8ac4d2fdeb08' 
  AND token = 'ILXBx2pvQaRTMQmghBQ1vW6L+YqjDDT3MLHKhTtiCVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}