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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7cd0c91d5eec397effe3efb1e3bb0d2fddcd0bc7629e2038dc0a8eb03d16a9a' 
  AND token = 'R/Ne9TOep+WHD7ou3vhrS4wujmqM8Rg13UgGPj2VI4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}