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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a50c9c56aff7ad6c76c2ab43d6e0839d8b7c728787e1ecf5355ab3e31688be6' 
  AND token = '9YX+1WrugrqqTKkbq1pDs2b5DSEZTxwSHl5Sn8J48UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}