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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e6c1a0fd6d145e2d834990b3d5950221c6d7950c32f045eb082edaf60ff653f' 
  AND token = '78PpBXxNN1rFm8ouLEtDp0YcyHzT82Nzbs4l1teSS/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}