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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491684869ae4e3584f7060b9f2c32bbffdbd31621ea68a0247e2c4c3bc205382' 
  AND token = 'mrUT04FDO0+KF+sQJTV1iTagZbXFpXcyVFZ4o6Px//w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}