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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f41b1ab2b3b573a750d452e66f40f1a29e0a4af3bbb27a7b0300edba925036e' 
  AND token = 'mznGypYS0r55tbaayrNgao+Dynh4lMIHj+2nKN9szSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}