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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82c3e8c07f6edf12f96f6ffcb43934fc7bb6d2e4a60734a9db9e56adde1ca339' 
  AND token = 'rMJAqkodZYoTzZukfmRaYvH1IA8aZmlYMsxZzMxw1Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}