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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bfa327c9c5559057b1ee074f9f83f81d841bbeef19c40e326b5575b69023716' 
  AND token = 'kSftVYgcyUkhk8sVkit8/wWUDBvkkGmEZyAtMX73EOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}