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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8367a62d161b90ada00a2ffa42e421718353bed60504fc7e221a1a6f1be8e20' 
  AND token = 'ZBts5FFTmT9rkWFu5vWjcsWP+dpIv2dfI0Nj9nTUYnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}