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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02177ace2a7ee3707f61db8cca81d4de3a31428f9f39a1bfb1cadb4c2a69097b' 
  AND token = 'r9Dyc3dJtkr360ejoB1dXMx+tl+X/YIQ21D6Ug//4hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}