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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0dcfbcd9e91919d0301d365a99f4a56797deb9f4789406104351b9b8e6e6ed' 
  AND token = 'UI7p1383sYuh6NLAqZ8THFd5KPKDejURuU2fi+JzgvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}