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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6a7fa4fd2a54c902dc8a687094997d2a4b05e0ff569e7ad7ccaaa21752e611' 
  AND token = 'AOUAwPo5GMM2eMpfOl87vmkxNg0McT0ZDJeNpbHmcOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}