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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb1bcb7263dba3e2581ac7c89c1f6a3fa25c080edb82881f7335dcba24634e83' 
  AND token = '0QwmZCtu4tb7i+LGKYGo6EUNkj2zlkDSsHZFy2ejLuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}