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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e29ce3f9b86d5911c6467e773c9789b7c043ba6d3532188204ab6acf4326e9' 
  AND token = 'uP+at1f6pK3j6Nug2lMGTKXR0FdBcgk2DkL3MhGVtTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}