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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61457f0b67b80ea3e210e4b7182b181205b88403f788a385fc39484365cdff1c' 
  AND token = '1ELO/wEZAoI533g2a6Y2CAsibBTGQTgITviZjuAwOos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}