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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c3d9e37d57cb80b042487a649dc8545c923069c08419b94dc10c083cb5b5fb' 
  AND token = 'mcE/QLNEYcMUAVDZWhRBxpv8xOSymWX+bPnB8a3eAuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}